PubMed Health⌕ Search

PubMed · 8465323

[Combination therapy with antidepressive agents--risks for interactions].

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

O Spigset. 1993-02-20. [Combination therapy with antidepressive agents--risks for interactions].. https://pubmed.ncbi.nlm.nih.gov/8465323/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

St. John's what?

Explore the source record for details and available documents.

Antidepressive Agents↗

High-performance liquid chromatography-electrospray ionization mass spectrometry method for the measurement of moclobemide and two metabolites in plasma.

A rapid and sensitive liquid chromatography-electrospray ionisation mass spectrometry (HPLC-ESI-MS) assay has been developed for the measurement of moclobemide and metabolites, Ro12-5637 and Ro12-8095, in human plasma. Sample preparation (0.5 ml plasma) involves solid-phase extraction using C18 cartridges. A Nova-Pak phenyl column (Waters, 4 microm, 150x2 mm I.D.) was employed for analyte separation with a mixture of 0.2 M ammonium formate buffer, pH 3.57 and acetonitrile as the mobile phase. The within- and between-day precisions of the assay were <18% and the limit of quantification for all analytes was 0.01 microg/ml. The total run-time was 6 min. The method described was used to measure moclobemide, Ro12-5637 and Ro12-8095 in human plasma following an oral 300 mg dose.

Antidepressive Agents↗