[Penicillamine-induced glomerulonephritis].

W Koall; E Mampel

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PubMed · 848141

[Penicillamine-induced glomerulonephritis].

W Koall·E Mampel

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Abstract

In 6 of 24 courses of a disease a nephrotic syndrome appeared under the application of penicillamine. An acute renal failure with exitus letalis developed under the penicillamine therapy of a scleroderma. In the treatment of a mercurial poisoning by penicillamine the nephrotic syndrome increased to a proteinuria of 50 g/24 hours which receded after discontinuation of the remedy. In one group of patients with chronic pyelonephritis could be demonstrated that penicillamine in a primarily damaged kidney must not lead to a secondary glomerular lesion. These findings led to the conclusion that in the appearance of a proteinuria under penicillamine a strong observation of the renal function is necessary, if a continution of the therapy is given from vital indication.

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Acute Kidney Injury Female Glomerulonephritis Humans Male Mercury Poisoning Middle Aged Nephrotic Syndrome Penicillamine Case Reports English Abstract Journal Article

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W Koall, E Mampel. 1977. [Penicillamine-induced glomerulonephritis].. https://pubmed.ncbi.nlm.nih.gov/848141/

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