A three compartment open model with two time lags.

Y Cherruault; V B Sarin

doi:10.1016/0020-7101(93)90019-3

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A three compartment open model with two time lags.

Y Cherruault·V B Sarin

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Abstract

The present study deals with the identification of exchange parameters involved in a three-compartment open model with two time lags in which elimination occurs from the central compartment. Two different optimization methods have been used which involve the reduction of different unknowns to a single variable theta, with the help of Archimedes Spiral. Thus, the solution requires the global minimum of a functional of single variable theta. Results are compared with those obtained by the generalized least square method.

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Y Cherruault, V B Sarin. 1993. A three compartment open model with two time lags.. https://doi.org/10.1016/0020-7101(93)90019-3

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