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Is the endolymphatic K secretion electrogenic?

E Ferrary·C Bernard·N Julien·O Sterkers·C Amiel
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Abstract

The endolymphatic potential is assumed to result from active K transport into the endolymphatic compartment and passive K diffusion in the opposite direction. However, in several in vivo experiments, changes in the endolymphatic potential differed from those in the endolymphatic K concentration. Moreover, in in vitro experiments, a negative endolymphatic potential was observed in the presence of ouabain without K gradient between the two compartments. These observations suggest that the coupling between the K transport and the genesis of the endolymphatic potential is not tight. Several factors may separately influence the endolymphatic potential and the K transport such as the acid-base equilibrium, the integrity of Reissner's membrane, the hormonal status, and the Na transport.

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AnimalsCochlear Microphonic PotentialsEndolymphIon TransportPotassiumRana esculentaSemicircular CanalsJournal ArticleResearch Support, Non-U.S. Gov't

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E Ferrary, C Bernard, N Julien, O Sterkers, C Amiel. 1993. Is the endolymphatic K secretion electrogenic?. https://doi.org/10.3109/00016489309135820

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