PubMed Health⌕ Search

PubMed · 8517285

MR angiography: present and future.

Abstract

MR angiography is a rapidly evolving technique for noninvasive vascular imaging. Since 1985, when it was first shown to be clinically feasibls, the imaging techniques and hardware used for MR angiography have greatly improved. No longer is MR angiography a mere academic curiosity; it is already widely used to diagnose stenoses of carotid bifurcations and intracranial aneurysms. MR angiography supplements, and in some cases supplants, duplex sonography and CT for the study of suspected venous thrombosis in the chest, abdomen, and pelvis. With continuing technical developments, MR angiography most likely will replace conventional X-ray angiography in the presurgical workup of patients who are candidates for carotid endarterectomy or liver transplantation. Even MR angiography of the coronary arteries, considered implausible just a few years ago, has become feasible with the implementation of fast imaging techniques that suppress artifacts from respiratory and cardiac motion. Nonetheless, substantial problems remain that must be overcome before the full clinical potential of MR angiography can be realized. Despite the superficial similarities between MR angiograms and conventional angiograms, fundamentally different features of blood vessels are depicted. MR angiography is susceptible to a variety of artifacts that can exaggerate or simulate pathologic changes. The patient's cooperation is essential. The spatial resolution of MR angiography is inferior to its conventional counterpart, although the gap is being narrowed. This article reviews the basic principles of MR angiography and flow artifacts and surveys existing and future clinical applications.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

R R Edelman. 1993. MR angiography: present and future.. https://doi.org/10.2214/ajr.161.1.8517285

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Striping artifact removal in VisiumHD data through nuclear counts modeling.

MOTIVATION: 10x Genomics VisiumHD enables spatial transcriptomics at 2 µm × 2 µm resolution but exhibits slide-specific, non-periodic striping artifacts due to lane-width variability. These multiplicative row/column effects distort bin total counts and can bias downstream analyses. The state-of-the-art destriping approach is the normalization procedure used as a preprocessing step in bin2cell; it applies sequential high-quantile row- then column-wise normalization, which is asymmetric and can introduce edge effects/macro-stripes and distortions of large-scale total-count structure. RESULTS: We propose a statistical destriping approach that leverages nuclei segmentation from the co-registered H&E image. Assuming transcript abundance is constant within each nucleus, we model bin counts with a negative binomial distribution whose mean is a product of a nucleus-specific concentration and row- and column-specific stripe-factors reflecting lane-width variation. We fit all parameters in a generalized linear modeling framework with cross-validated regularization on stripe-factors and iterative dispersion estimation, and use the fitted parameters to correct the observed counts into a destriped image. On synthetic data with known ground truth, our method improves stripe-factor estimation accuracy and reduces error in corrected counts relative to bin2cell and bin2cell-derived baselines. Across four public VisiumHD slides, it consistently lowers striping intensity while substantially better preserving biological signal present in the large-scale global count structure and avoiding the artifacts introduced by other methods. AVAILABILITY AND IMPLEMENTATION: All source code and links to publicly available data used for this study are available at https://github.com/paolamalsot/destriping-GLM.

Artifacts↗

Impairment of echocardiographic acoustic window caused by breast implants.

Cosmetic breast implants are increasing in popularity. The presence of a breast implant overlying the anterior mediastinal space as a cause of impairment of the echocardiographic acoustic window has not been described previously. Here, we report three cases with significant impairment of echocardiographic acoustic window caused by breast implants. Clinicians should be aware of this interference and women should be informed of this dilemma before considering this cosmetic surgery.

Artifacts↗