Extracellular matrix-cell interactions and chondrogenesis.

D Huang

PubMed · 852175

Extracellular matrix-cell interactions and chondrogenesis.

Abstract

Extracellular matrix macromolecules are capable of complex interactions. Recent studies demonstrate that extracellular matrix macromolecules can regulate the synthesis of chrondroitin sulfate by chondrocytes. Extracellular chondroitin sulfate stimulates chondroitin sulfate synthesis, whereas external hyaluronic acid inhibits chondroitin sulfate production. Other matrix macromolecule-cell interactions are reviewed. An hypothesis is proposed to account for the interaction between the cell and its extracellular matrix macromolecules.

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Cartilage Cells, Cultured Chondroitin Chondroitin Sulfates Collagen Glycoproteins Humans Hyaluronic Acid Lymphocyte Activation Macromolecular Substances Proteoglycans Journal Article Research Support, U.S. Gov't, P.H.S.

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D Huang. Extracellular matrix-cell interactions and chondrogenesis.. https://pubmed.ncbi.nlm.nih.gov/852175/

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