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Ageing, oscillations and efficiency.

D A Gilbert
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Abstract

The phenomenon of ageing still defies understanding. Theoretical studies have indicated that glycolysis is more efficient at maintaining a high ATP/ADP ratio when oscillating at its resonant frequency. Earlier, it was proposed that the differentiated state results from the establishment of a stable pattern of temporal organisation. It is now suggested that ageing involves a decrease in efficiency due to the detuning of oscillating glycolysis as a result of frequency locking with other cellular oscillations in the differentiated state.

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Adenosine DiphosphateAdenosine TriphosphateAgingAnimalsCell DifferentiationGlycolysisHumansModels, BiologicalOscillometryJournal ArticleReview

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BibTeXRIS

D A Gilbert. 1995. Ageing, oscillations and efficiency.. https://doi.org/10.1016/0303-2647(94)01491-o

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