Detection of secondary amines on solid phase.

T Vojkovsky

PubMed · 8527877

Detection of secondary amines on solid phase.

Abstract

The detection of secondary amino groups in building blocks attached to solid phase using tetrachlorobenzoquinone (chloranil) was re-examined. A new procedure, about ten times more sensitive than the original method, has been developed. Except for N(p-tolyl)glycine, all secondary amino groups that were examined were detected reliably in a substitution range down to 2.8 micro eq/g. Protected imidazole in His(Trt) did not interfere with the detection method.

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T Vojkovsky. Detection of secondary amines on solid phase.. https://pubmed.ncbi.nlm.nih.gov/8527877/

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