Electrotonic coupling between two CA3 hippocampal pyramidal neurons: a distributed cable model with somatic gap-junction.

R R Poznanski; W G Gibson; M R Bennett

doi:10.1007/bf03354909

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Electrotonic coupling between two CA3 hippocampal pyramidal neurons: a distributed cable model with somatic gap-junction.

R R Poznanski·W G Gibson·M R Bennett

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Abstract

A model of a pair of electrotonically coupled CA3 hippocampal pyramidal neurons is presented. Each neuron is represented by a tapered equivalent cable attached to an isopotential soma. The synaptic potential in a neuron soma is determined as a consequence of electrical coupling to another soma that receives a synaptic input on its dendritic tree. Estimates of the coupling resistances, soma input resistances and soma-to-dendritic tree conductance ratio show that a substantial current may arise in a neuron as a consequence of synaptic activity in a neuron coupled to it. The small increase in decay time due to coupling in the model indicates that actual coupling is between more than just pairs of neurons.

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Animals Cell Communication Gap Junctions Hippocampus Mammals Mathematics Membrane Potentials Models, Neurological Pyramidal Cells Synapses Journal Article Research Support, Non-U.S. Gov't

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R R Poznanski, W G Gibson, M R Bennett. 1995. Electrotonic coupling between two CA3 hippocampal pyramidal neurons: a distributed cable model with somatic gap-junction.. https://doi.org/10.1007/bf03354909

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