Native-like and structurally characterized designed alpha-helical bundles.

S F Betz; J W Bryson; W F DeGrado

doi:10.1016/0959-440x(95)80029-8

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Native-like and structurally characterized designed alpha-helical bundles.

S F Betz·J W Bryson·W F DeGrado

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Abstract

A number of coiled coils and alpha-helical bundles have recently been designed, and many have now been structurally characterized by X-ray crystallography. Others have not been as well characterized structurally but exhibit native-like properties in aqueous solution. Both areas of investigation have contributed greatly to our understanding of the nature of specificity in this class of molecules.

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Amino Acid Sequence Crystallography, X-Ray Molecular Sequence Data Protein Conformation Protein Structure, Secondary Solutions Journal Article Review

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S F Betz, J W Bryson, W F DeGrado. 1995. Native-like and structurally characterized designed alpha-helical bundles.. https://doi.org/10.1016/0959-440x(95)80029-8

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