Mouse T-cell receptor variable gene segment families.

B Arden; S P Clark; D Kabelitz; T W Mak

doi:10.1007/bf00172177

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PubMed · 8550093

Mouse T-cell receptor variable gene segment families.

B Arden·S P Clark·D Kabelitz·T W Mak

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Abstract

All mouse T-cell receptor alpha/delta, beta, and gamma variable (Tcra/d-, b-, and g-V) gene segments were aligned to compare the sequences with one another, to group them into subfamilies, and to derive a name which complies with the standard nomenclature. It was necessary to change the names of some V gene segments because they conflicted with those of other segments. The traditional classification into subfamilies was re-evaluated using a much larger pool of sequences. In the mouse, most V gene segments can be grouped into subfamilies of closely related genes with significantly less similarity between different subfamilies.

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Amino Acid Sequence Animals Base Sequence Mice Molecular Sequence Data Receptors, Antigen, T-Cell, alpha-beta Receptors, Antigen, T-Cell, gamma-delta Sequence Alignment Terminology as Topic Journal Article Review

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B Arden, S P Clark, D Kabelitz, T W Mak. 1995. Mouse T-cell receptor variable gene segment families.. https://doi.org/10.1007/bf00172177

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