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Prospects for new vaccines against tuberculosis.

I M Orme
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Abstract

The spectacular failure of the existing bacille Calmette-Guérin (BCG) vaccine in recent tuberculosis-control trials has prompted a search for potential replacements. Imaginative approaches currently under development include the modulation of BCG by the production of auxotrophic mutants or cytokine-secreting recombinants, and the development of subunit vaccines based on the major proteins of Mycobacterium tuberculosis.

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Adjuvants, ImmunologicAnimalsBacterial VaccinesHumansMycobacterium bovisMycobacterium tuberculosisTuberculosisJournal ArticleResearch Support, U.S. Gov't, P.H.S.Review

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BibTeXRIS

I M Orme. 1995. Prospects for new vaccines against tuberculosis.. https://doi.org/10.1016/s0966-842x(00)88987-8

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