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MITOMAP: a human mitochondrial genome database.

A M Kogelnik·M T Lott·M D Brown·S B Navathe·D C Wallace
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Abstract

We have developed a comprehensive database (MITOMAP) for the human mitochondrial DNA (mtDNA), the first component of the human genome to be completely sequenced [Anderson et al. (1981) Nature 290, 457-465]. MITOMAP uses the mtDNA sequence as the unifying element for bringing together information on mitochondrial genome structure and function, pathogenic mutations and their clinical characteristics, population associated variation, and gene- gene interactions. As increasingly larger regions of the human genome are sequenced and characterized, the need for integrating such information will grow. Consequently, MITOMAP not only provides a valuable reference for the mitochondrial biologist, it may also provide a model for the development of information storage and retrieval systems for other components of the human genome.

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Amino Acid SequenceBase SequenceComputer Communication NetworksDNA, MitochondrialDatabases, FactualGenome, HumanHumansMutationJournal ArticleResearch Support, Non-U.S. Gov'tResearch Support, U.S. Gov't, P.H.S.

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A M Kogelnik, M T Lott, M D Brown, S B Navathe, D C Wallace. 1996-01-01. MITOMAP: a human mitochondrial genome database.. https://doi.org/10.1093/nar%2F24.1.177

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