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PubMed · 8634364

Two-neuro networks. II. Leaky integrator pacemaker models.

L Gómez·R Budelli
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Abstract

The behavior of two pacemaker neurons simulated by leaky integrators and connected reciprocally by synapses was studied. In every case the firing of both neurons phase-locks. The resulting limit cycle may or may not show simultaneous firing of both neurons. When both synapses are excitatory, phase-locking with simultaneous neuronal firing is always present. When one synapse is excitatory and the other inhibitory, phase-locking is also present always, while the neurons may or may not fire simultaneously. For a restricted set of parameters, bistability appears; the initial conditions determine whether or not the limit cycle presents simultaneous firing. When both synapses are inhibitory, the system phase-locks without simultaneous firing for almost every set of parameters.

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Biological ClocksComputer SimulationMathematicsMembrane PotentialsModels, NeurologicalNeuronsJournal ArticleResearch Support, Non-U.S. Gov't

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L Gómez, R Budelli. 1996. Two-neuro networks. II. Leaky integrator pacemaker models.. https://pubmed.ncbi.nlm.nih.gov/8634364/

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