Controlling IGF-receptor function: a possible strategy for tumor therapy.

R Baserga

doi:10.1016/0167-7799(96)10023-8

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Controlling IGF-receptor function: a possible strategy for tumor therapy.

R Baserga

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Abstract

The insulin-like growth factor-1 receptor (IGF-IR) is one of several growth-factor receptors that regulate the proliferation of mammalian cells. However, its ubiquitousness and certain unique aspects of its function make IGF-IR an ideal target for therapeutic interventions against abnormal growth, with very little effect on normal cells.

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Animals Biotechnology Genetic Therapy Neoplasms, Experimental Receptor, IGF Type 1 Journal Article Review

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R Baserga. 1996. Controlling IGF-receptor function: a possible strategy for tumor therapy.. https://doi.org/10.1016/0167-7799(96)10023-8

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