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PubMed · 8670264

Dynamin II binds to the trans-Golgi network.

O Maier·M Knoblich·P Westermann
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Abstract

Two dynamin II-specific antibodies were used to detect dynamin II attached to highly purified Golgi membranes of HepG2 cells. Within the Golgi apparatus dynamin II is predominantly localized to the trans-Golgi network, as shown by immunoelectron microscopy. Increased binding of dynamin II to the trans-Golgi network in the presence of GTP-gamma-S and a reduced binding upon stimulation of secretion by phorbolester indicates that dynamin II may have a function in post-Golgi vesicle transport.

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Amino Acid SequenceAnimalsAntibodiesBlotting, WesternCell LineDynaminsElectrophoresis, Polyacrylamide GelGTP PhosphohydrolasesGolgi ApparatusGuanosine 5'-O-(3-Thiotriphosphate)HumansIntracellular MembranesMicroscopy, ImmunoelectronMicrotubulesMolecular Sequence DataPeptide FragmentsRabbitsTumor Cells, CulturedJournal ArticleResearch Support, Non-U.S. Gov't

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O Maier, M Knoblich, P Westermann. 1996-06-14. Dynamin II binds to the trans-Golgi network.. https://doi.org/10.1006/bbrc.1996.0876

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