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PubMed · 8691603

[Amines and pteridines].

K Shimpo·T Chihara·M Hibiya·S Ito·T Nagatsu
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Abstract

Polyamines (putrescine, spermidine and spermine) play important roles in cell proliferation and differentiation, and have been established as tumors markers. We and other workers have confirmed that N1-acetylspermidine in tumor tissues, spermidine and spermine in erythrocytes, and N1,N12-diacetylspermine in urine might be the most sensitive indicators for various forms of tumors. Neopterin is a marker of cell-mediated immunostimulation, and may be a helpful marker in monitoring cancer patients. HPLC and immunological assays of neopterin, biopterin, and N2-(3-aminopropyl)biopterin(oncopterin) in urine might be useful in the clinical study of pteridines, as cancer markers. Serum 5-S-cysteinyldopa level is a useful and specific biochemical marker for malignant melanoma.

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Biomarkers, TumorBiopterinsCysteinyldopaHumansMelanomaNeoplasmsNeopterinPolyaminesEnglish AbstractJournal ArticleReview

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K Shimpo, T Chihara, M Hibiya, S Ito, T Nagatsu. 1996. [Amines and pteridines].. https://pubmed.ncbi.nlm.nih.gov/8691603/

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