PubMed HealthSearch

PubMed · 8700715

Stroke. Communication difficulties.

Abstract

This paper highlights the problem of non-fluid dysphasia and provides an overview of the complex physical, psychological and social dimension to consider when caring for this client group.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

C Moules. Stroke. Communication difficulties.. https://pubmed.ncbi.nlm.nih.gov/8700715/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Multiple exon screening using restriction endonuclease fingerprinting (REF): detection of six novel mutations in the L1 cell adhesion molecule (L1CAM) gene.

Restriction endonuclease fingerprinting (REF) has been utilized to screen 19 of the 28 exons in the L1CAM gene using only 5 PCR reactions. The clustered exons were amplified and the PCR products were subjected to endonuclease digestion and subsequent gel electrophoresis to produce a highly informative fingerprint for each PCR product. An alteration in the fingerprint, when compared to a control, determined the specific DNA fragment containing the mutation. Sequencing of the corresponding exon and flanking region was done to determine the precise location of the mutation. Using this method we have identified 6 novel mutations in the L1CAM gene in 5 patients with X-linked hydrocephalus and 2 patients with MASA. One of the mutations was common to both a patient with HSAS and a patient with MASA. The utilization of REF will allow for easier and quicker detection of mutations in the L1CAM gene. This method should be applicable for screening other genes with multiple, clustered exons.

Aphasia

Aphasia diagrams: a new notational scheme for representing neurolinguistic deficits.

Models of language processing are becoming extremely complex. As a result, it has become very difficult to develop a thorough understanding of even a single patient's deficits, let alone to represent those deficits in a way which renders their significance apparent to others. In this paper, we describe and demonstrate the use of a notational system which has been developed specifically for representing the complexities of neurolinguistic deficits. The notational system is simple to learn and to use and may easily be extended and adapted to different models of language processing. It may also be used to represent the results from other nonlinguistic neuropsychological batteries which are composed of tightly interdependent subtests with many related factors included in each subtest. Despite its simplicity, the notational system has proven itself in the field as a useful tool for rendering complex deficits more easily interpretable.

Aphasia

Semantic transparency in the processing of compounds: consequences for representation, processing, and impairment.

The role of semantic transparency in morphological processing in general and in compound processing in particular is examined. It is argued that the notion of semantic transparency is crucial to an account of how compounds are represented and processed in the mind. A sketch of a model is proposed in which compound processing is described in terms of stimulus properties, lexical properties, and conceptual properties. The model represents the notion of semantic transparency in terms of a four-way classification of the semantic relationship between a compound's constituents and the corresponding independent morphemes. It also distinguishes between semantically componential and noncomponential compounds. It is proposed that the model offers a framework within which experimental psycholinguistic findings can be understood and within which aphasic deficits associated with compound processing can be characterized. As an example of this, the paper presents a reanalysis of an aphasic patient who exhibits the tendency to interpret semantically opaque compounds as though they were transparent and to interpret opaque compounds in terms of a blend of constituent and whole-word meaning. It is argued that the underlying deficit in this patient is the failure for inhibition to result from the competition among stimuli at the conceptual level of representation.

Aphasia