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PubMed · 8701773

[Microdialysis sampling and microbore liquid chromatography with electrochemical detection for determination of serotonin in rat brain striatum].

F M Xie·T H Huang·P T Kissinger
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Abstract

AIM: To develop a sensitive method for determination of serotonin in biological samples. METHODS: A combination of microdialysis sampling and microbore liquid chromatography with electrochemical detection (LCEC) was established. RESULTS: Changes of serotonin in fg or pg in microdialysates from brain striatum of the free moving rat were easily determined. CONCLUSION: This developed method was useful for living animal research. Serotonin level in corpus striatum healthy rats was quite stable.

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AnimalsChromatography, LiquidCorpus StriatumMicrodialysisRatsRats, WistarSerotoninEnglish AbstractJournal Article

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F M Xie, T H Huang, P T Kissinger. 1995. [Microdialysis sampling and microbore liquid chromatography with electrochemical detection for determination of serotonin in rat brain striatum].. https://pubmed.ncbi.nlm.nih.gov/8701773/

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