PubMed · 8705453
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M Takahashi, T Eto, Y Ichiba, T Nishida. 1996. [Ischemic cholecystitis].. https://pubmed.ncbi.nlm.nih.gov/8705453/
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BACKGROUND: The purpose of this study is to define the sensitivity and specificity of the gallbladder ejection fraction (GBEF) for identifying patients with various grades of histologically proven chronic cholecystitis. METHODS: Of 693 consecutive patients who had a scintigraphic GBEF determination at Baptist Medical Center of Oklahoma, 161 subsequently had a cholecystectomy at the same institution. Pathologic material was reassessed by one outside blinded reviewer, who graded the intensity of the inflammation present on a 0 (absent) to 3 (most severe) scale. RESULTS: The least square mean maximum GBEF was 23.7% for those with grade 0, 9.6% for those with grade 3, and 13.9% for those with cholesterolosis. If a normal value for GBEF is set at > 30%, the sensitivity for detecting grade 1, 2, or 3 disease was 84%, and the specificity was 26%. For grade 3 disease alone, the sensitivity was 100%, and the specificity was 26%. CONCLUSIONS: The GBEF is sensitive but not specific for chronic inflammation of the gallbladder. The GBEF appears to be useful as a screening examination in the appropriate clinical setting.
AIM: The study of lipid fraction spectrum in plasma of patients with chronic calculous cholecystitis (CCC) before and after the operative intervention. MATERIALS AND METHODS: 28 female patients with CCC. Plasma lipids were measured before the operation, 1 and 5 days after it, at the discharge from hospital and in healthy donors. RESULTS: Before the operation blood concentrations of total lipids, triacylglycerins, phosphatidylcholine and phosphatidylethanolamine were elevated. Cholesterol, lisophosphatidylcholine and sphingomyelin, cholesterol/phospholipids ratio were subnormal. The same changes of the lipids persisted 1 and 5 days after the surgery and at discharge. CONCLUSION: Plasma lipids in CCC patients are not corrected early after the surgery and require drug correction.
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