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BCR/ABL and leukemia.

A Butturini·R B Arlinghaus·R P Gale
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Abstract

This review focuses on the role of the chimeric BCR/ABL gene in leukemia development. First, we discuss and update knowledge regarding the molecular biology of BCR/ABL. We then review data regarding transforming activity of BCR/ABL. Third, we discuss the complex interactions between BCR/ABL and leukemia phenotype. We conclude with a brief discussion of possible therapeutic implications of these data.

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AnimalsFusion Proteins, bcr-ablHumansLeukemiaJournal ArticleReview

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BibTeXRIS

A Butturini, R B Arlinghaus, R P Gale. 1996. BCR/ABL and leukemia.. https://doi.org/10.1016/0145-2126(95)00057-7

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