5-Hydroxytryptamine in the central nervous system.

E Chojnacka-Wójcik

PubMed · 8714755

5-Hydroxytryptamine in the central nervous system.

Abstract

The review summarizes the results of studies into the role of 5-HT as a neurotransmitter in the central nervous system. The biosynthesis, release, metabolism and distribution of 5-HT; classification and localization of 5-HT receptors; electrophysiological effects of 5-HT and its influence on second messengers; autoregulation of 5-HT release; effects of 5-HT on the release of other neurotransmitters and pituary hormones; behavioral effects induced by 5-HT receptor agonists and the functional interaction between different receptor subtypes have been described. Additionally, some data on functional changes in the 5-HT system in psychiatric disorders have been cited, and a possibility of clinical utilization of 5-HT-active related drugs in neuropsychiatric and other diseases has been reviewed.

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Alzheimer Disease Brain Chemistry Depression Humans Receptors, Serotonin Schizophrenia Serotonin Journal Article Review

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E Chojnacka-Wójcik. 5-Hydroxytryptamine in the central nervous system.. https://pubmed.ncbi.nlm.nih.gov/8714755/

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