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PubMed · 8734332

[Current therapeutic methods in onco-hematology].

I Madelaine-Chambrin·V Piquet-Sevrin·P Faure
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Abstract

These next years, many anticancer drugs will be available with new mechanism of action. The taxoïd compounds: Taxol and Taxotere have been judged efficous in the treatment of advanced ovary and breast cancers. Also, DNA-Topoisomerase I inhibitors, a new enzyme molecular target, will expand solid tumors therapeutic strategies. The adenosine analogs represent the xnewest advances in hematology: fludarabine becomes the second line treatment for chronic lymphoïd leukemia, cladribine the reference treatment for hairy cell leukemia. At least, all-trans retinoïc acid has changed acute promyelocytic leukemia pronostic by differentiating tumor cells, and open a very new way of cancer treatment. All these agents are the first compounds available, others are still in development. They, all, are benefit of a productive research.

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Antineoplastic AgentsAntineoplastic Agents, PhytogenicCladribineDocetaxelHumansKeratolytic AgentsLeukemiaPaclitaxelTaxoidsTopoisomerase I InhibitorsTretinoinVidarabineJournal ArticleReview

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BibTeXRIS

I Madelaine-Chambrin, V Piquet-Sevrin, P Faure. 1996. [Current therapeutic methods in onco-hematology].. https://pubmed.ncbi.nlm.nih.gov/8734332/

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