The puzzling origin of the genetic code.

R Cedergren; P Miramontes

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PubMed · 8744351

The puzzling origin of the genetic code.

R Cedergren·P Miramontes

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Abstract

Recent results add to the mystery of the origin of the genetic code. In spite of early doubts, RNA can discriminate between hydrophobic amino acids under certain contexts. Moreover, codon reassignment, which has taken place in several organisms and mitochondria, is not a random process. Finally, phylogenies of some aminoacyl-tRNA synthetases suggest that the entire code was not completely assigned at the time of the divergence of bacteria from nucleated cells.

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Amino Acids Amino Acyl-tRNA Synthetases Codon Evolution, Molecular Genetic Code Oligoribonucleotides Phylogeny RNA RNA, Transfer Journal Article Research Support, Non-U.S. Gov't

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R Cedergren, P Miramontes. 1996. The puzzling origin of the genetic code.. https://pubmed.ncbi.nlm.nih.gov/8744351/

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