Structure-activity studies using valence molecular connectivity.

L H Hall; L B Kier

doi:10.1002/jps.2600660509

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Structure-activity studies using valence molecular connectivity.

L H Hall·L B Kier

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Abstract

The extension of the molecular connectivity concept to the treatment of heteroatom molecules affords an opportunity to examine structure-activity relationships in a wide variety of molecule series that possess biological activity. Four series are described in this report. The correlations found indicate that molecular connectivity is an extremely useful descriptor of structure in studying drug molecule structure-activity relationships.

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Aniline Compounds Animals Aspergillus niger Benzyl Alcohols Cytochromes Elementary Particles Houseflies In Vitro Techniques Liver Organophosphorus Compounds Phenols Rabbits Structure-Activity Relationship Taste Journal Article

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L H Hall, L B Kier. 1977. Structure-activity studies using valence molecular connectivity.. https://doi.org/10.1002/jps.2600660509

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