PubMed · 8762906
[Corneal abscess: therapeutic attitude based on microbiological testing].
Abstract
PURPOSE: Bacterial corneal ulcers can affect the integrity of the eye and need therefore to be treated following strict rules. The authors present a prospective study on 15 bacterial corneal ulcers for which the initial treatment with topical fortified antibiotics was guided according to the results of Gram stain. MATERIAL AND METHODS: Gram positive cocci ulcers were treated with vancomycine (5 cases), Gram negative rod ulcers with gentamycine and ticarcilline (2 cases), and the association of these 3 antibiotics was used when no bacteria was found (8 cases). RESULTS: The results of the Gram stain and the culture were consistent in all the cases. Mean healing time was statistically significantly shorter when an infectious agent was found on Gram stain (13 days) than when not (23 days). CONCLUSION: These results suggest that the prognosis of bacterial corneal ulcers is enhanced when infectious agents are recovered and that the strategy of initiating an antibiotic therapy adapted to the gram stain results appears reliable and efficient. The successful outcome of this approach needs a perfect collaboration with the microbiologist.
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B Briat, T Hoang-Xuan. 1996. [Corneal abscess: therapeutic attitude based on microbiological testing].. https://pubmed.ncbi.nlm.nih.gov/8762906/
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