Orificial tuberculosis: detection by polymerase chain reaction.

F Nachbar; V Classen; T Nachbar; M Meurer; C G Schirren; K Degitz

doi:10.1046/j.1365-2133.1996.d01-943.x

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PubMed · 8776370

Orificial tuberculosis: detection by polymerase chain reaction.

F Nachbar·V Classen·T Nachbar·M Meurer·C G Schirren·K Degitz

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Abstract

Orificial tuberculosis (OT) is a rare manifestation of cutaneous tuberculosis in immunocompromised individuals. Due to its variable clinical features, the diagnosis may be missed at the onset of the disease. We report a 53-year-old patient who had OT and miliary spread of Mycobacterium tuberculosis to the lungs, liver, bones and skin. The diagnosis was established by polymerase chain reaction (PCR) amplification of a Mycobacterium-specific gene segment, and confirmed by culture. PCR allows the detection of mycobacterial DNA within a few days, whereas culture takes many weeks. PCR may improve the accurate diagnosis of skin tuberculosis and allow early treatment.

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Base Sequence DNA, Bacterial Humans Male Middle Aged Molecular Sequence Data Mycobacterium tuberculosis Polymerase Chain Reaction Tuberculosis, Cutaneous Tuberculosis, Oral Case Reports Journal Article

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F Nachbar, V Classen, T Nachbar, M Meurer, C G Schirren, K Degitz. 1996. Orificial tuberculosis: detection by polymerase chain reaction.. https://doi.org/10.1046/j.1365-2133.1996.d01-943.x

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