Programmed cell death in invertebrates.

M O Hengartner

doi:10.1016/s0959-437x(96)90007-6

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PubMed · 8791487

Programmed cell death in invertebrates.

M O Hengartner

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Abstract

Genetic studies of programmed cell death in Caenorhabditis elegans and Drosophila melanogaster have led to the identification of several invertebrate cell death genes. In C. elegans, ced-3 and ced-4 function to kill cells, whereas ced-9 protects cells from death. In Drosophila, the genes reaper and hid act in parallel to promote cell death. Characterization of these genes has revealed that the process of programmed cell death is evolutionarily conserved and has shed light on the molecular nature of the apoptotic machinery.

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Animals Apoptosis Caenorhabditis elegans Drosophila Humans Invertebrates Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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M O Hengartner. 1996. Programmed cell death in invertebrates.. https://doi.org/10.1016/s0959-437x(96)90007-6

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