PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 8821153

Dermatophytes: gross and microscopic.

I Weitzman·A A Padhye
View original source ↗Export metadata ↓

Abstract

Dermatophytes, members of the anamorphic genera Epidermophyton, Microsporum, and Trichophyton, are capable of invading keratinous tissue, causing cutaneous infection referred to as dermatophytosis. These species may be anthropophilic, zoophilic, or geophilic based on host preference and natural habitat. These groupings are epidemiologically significant. This article provides a description of the genera and species of the dermatophytes--gross and microscopic--and the tests that may be necessary to confirm their identification.

Explore related subjects

ArthrodermataceaeDermatomycosesHumansJournal ArticleReview

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

I Weitzman, A A Padhye. 1996. Dermatophytes: gross and microscopic.. https://doi.org/10.1016/s0733-8635(05)70320-x

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Analysis of the dermatophyte Trichophyton rubrum expressed sequence tags.

BACKGROUND: Dermatophytes are the primary causative agent of dermatophytoses, a disease that affects billions of individuals worldwide. Trichophyton rubrum is the most common of the superficial fungi. Although T. rubrum is a recognized pathogen for humans, little is known about how its transcriptional pattern is related to development of the fungus and establishment of disease. It is therefore necessary to identify genes whose expression is relevant to growth, metabolism and virulence of T. rubrum. RESULTS: We generated 10 cDNA libraries covering nearly the entire growth phase and used them to isolate 11,085 unique expressed sequence tags (ESTs), including 3,816 contigs and 7,269 singletons. Comparisons with the GenBank non-redundant (NR) protein database revealed putative functions or matched homologs from other organisms for 7,764 (70%) of the ESTs. The remaining 3,321 (30%) of ESTs were only weakly similar or not similar to known sequences, suggesting that these ESTs represent novel genes. CONCLUSION: The present data provide a comprehensive view of fungal physiological processes including metabolism, sexual and asexual growth cycles, signal transduction and pathogenic mechanisms.

Arthrodermataceae↗