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Increased hippocampal acetylcholine release during a working memory task.

F Fadda·F Melis·R Stancampiano
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Abstract

In this study we examined whether the food-reinforced alternation performance was associated with increased acetylcholine output in the dorsal hippocampus. Rats were trained to acquire the task using a T-maze. The control group consisted of rats introduced into the T-maze to run only on the day of dialysis. Acetylcholine release increased significantly in control rats only in the first 10 min after they were put into the T-maze. In trained rats acetylcholine output increased in the waiting cage as well as during trials in the T-maze. The increase in acetylcholine output in rats that had learned the task was significantly greater than in control rats.

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AcetylcholineAnimalsChromatography, High Pressure LiquidHippocampusMaleMaze LearningMemoryMicrodialysisRatsRats, Sprague-DawleyReinforcement, PsychologyJournal Article

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BibTeXRIS

F Fadda, F Melis, R Stancampiano. 1996-06-27. Increased hippocampal acetylcholine release during a working memory task.. https://doi.org/10.1016/0014-2999(96)00289-0

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