PubMed Health⌕ Search

PubMed · 884367

[Anatomical and clinical correlates statistical analysis].

Abstract

A retrospective study of the clinico-pathological correlation was undertaken on 1000 consecutive autopsies required by a university department of medicine. For each case the following data were collected on a standardized card: information on the patient, the hospital stay, the therapy; the main clinical and pathological diagnoses, classified according to their importance; judgements on the clinico-pathological correlation related to each single diagnosis as well as to each case as a whole. The data were analyzed by computer. Two samples of the results are presented her. 1. 18 cases of active tuberculosis were observed. In 7, among which 5 were autopsy discoveries, the tuberculosis was rated as the cause of death. 2. General estimate of clinico-pathological correlation. In the cases where the clinical picture was obscure the autopsy was able to solve the problem completely in 2 cases out of 3. Even when the clinival situation was thought to be obvious, the post mortem examination brought to light important errors or omissions in just over 30% of the cases. On ther other hand, in one case out of 10, the autopsy could not solve in part or in whole the clinical problems involved. There results show that routine autopsies are generally still useful today, but fail fairly ofter to meet the clinician's expectation. These failures can probably be in part corrected.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

D Gardiol, L Chamot, P Y Chamot, P h Haldy. 1977. [Anatomical and clinical correlates statistical analysis].. https://pubmed.ncbi.nlm.nih.gov/884367/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Langerhans cell histiocytosis infiltration into pancreas and kidney.

An 18-month-old male presented with a swelling of the neck for 2 months. A presumptive diagnosis of Langerhans cell histiocytosis (LCH) was made on fine needle aspiration cytology from the lymph node. The child received chemotherapy. He remained well for around 10 months, when he represented with loose stools, cough, and respiratory distress. His condition deteriorated over a few hours culminating in death. A partial autopsy revealed LCH infiltration in liver, pancreas, and kidneys along with bronchopneumonia. The pancreatic and renal infiltration by LCH is extremely rare.

Autopsy↗

Radiography after unexpected death in infants and children compared to autopsy.

BACKGROUND: Postmortem radiography may reveal skeletal and soft-tissue abnormalities of importance for the diagnosis of cause of death. OBJECTIVE: To review the radiographs of children under 3 years of age who had died suddenly and unexpectedly. To compare the radiological and autopsy findings evaluating possible differences in children dying of SIDS and of an explainable cause. MATERIALS AND METHODS: A total of 110 consecutive skeletal surveys performed between 1998 and 2002 were reviewed. All but one were performed before autopsy and comprised AP views of the appendicular and axial skeleton and thorax/abdomen, lateral views of the axial skeleton and thorax, and two oblique views of the ribs. Radiography and autopsy findings were compared. RESULTS: Causes of death were classified as SIDS/borderline SIDS (n = 52) and non-SIDS (n = 58), with one case of abuse. In 102 infants there were 150 pathological findings, 88 involving the chest, 24 skeletal, and 38 miscellaneous findings. The radiological-pathological agreement was poor concerning pulmonary findings. Skeletal findings were sometimes important for the final diagnosis. CONCLUSIONS: Radiography revealed many skeletal and soft-tissue findings. Pulmonary pathology was most frequently found, but showed poor agreement with autopsy findings. Recognizing skeletal findings related to abuse is important, as these may escape recognition at autopsy.

Autopsy↗

Autopsy-proven Huntington's disease with 29 trinucleotide repeats.

Huntington's disease (HD) is a neurodegenerative disorder associated with expansion of CAG trinucleotide repeats in the huntingtin gene. A minimum of 36 CAG repeats is usually reported in patients with clinical features of HD; 30 to 35 repeats represent an intermediate range. Here we report a 65-year-old male with autopsy-proven HD and 29 CAG repeats.

Autopsy↗