Leukocytes in capillary flow.

G W Schmid-Schönbein; J Lee

doi:10.1159/000179027

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PubMed · 8852624

Leukocytes in capillary flow.

G W Schmid-Schönbein·J Lee

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Abstract

During disease, the flow of blood cells through the capillary network is one of the most perilous events in the microcirculation. Capillary distensibility, cytoplasmic activity of endothelial cells, red cells and leukocytes play an important role in capillary perfusion. Occlusion of capillaries is one of the early signs of vascular failure and is encountered in many different conditions and organs. Adhesion of leukocytes to the endothelium via expression of membrane adhesion molecules leads to microvascular entrapment with capillary occlusion.

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Animals Blood Flow Velocity Capillaries Cell Adhesion Cell Aggregation Endothelium, Vascular Leukocytes Microcirculation Microscopy, Electron Microscopy, Electron, Scanning Neutrophils Rats Regional Blood Flow Journal Article Research Support, U.S. Gov't, P.H.S.

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G W Schmid-Schönbein, J Lee. Leukocytes in capillary flow.. https://doi.org/10.1159/000179027

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