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PubMed · 8895453

Patterning the vertebrate neuraxis.

A Lumsden·R Krumlauf
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Abstract

Neuraxial patterning is a continuous process that extends over a protracted period of development. During gastrulation a crude anteroposterior pattern, detectable by molecular markers, is conferred on the neuroectoderm by signals from the endomesoderm that are largely inseparable from those of neural induction itself. This coarse-grained pattern is subsequently reinforced and refined by diverse, locally acting mechanisms. Segmentation and long-range signaling from organizing centers are prominent among the emerging principles governing regional pattern.

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AnimalsBody PatterningCentral Nervous SystemEmbryonic InductionGene Expression Regulation, DevelopmentalGenes, HomeoboxMesencephalonMesodermNeuronsProsencephalonRhombencephalonSignal TransductionSpinal CordTretinoinJournal ArticleReview

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BibTeXRIS

A Lumsden, R Krumlauf. 1996-11-15. Patterning the vertebrate neuraxis.. https://doi.org/10.1126/science.274.5290.1109

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