[Essential hypertension].

K Ando; T Fujita

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PubMed · 8904235

[Essential hypertension].

K Ando·T Fujita

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Abstract

Abnormal membrane sodium transport system is a hypothesis that might explain the mechanism of pathophysiology of essential hypertension. Increased intracellular sodium concentration, which is induced by altered function in either Na+ -K+ pump, Na+ -K+ cotransport, Na+ -Li+ countertransport, or Na+ -H+ antiport, may increased intracellular calcium ion and cause vasoconstriction. Increased intracellular pH by enhanced Na+ -H+ antiport may also play an important role of increment of vascular tone in hypertension.

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Animals Blood Pressure Humans Hypertension Ion Transport Sodium Sodium-Hydrogen Exchangers Sodium-Potassium-Exchanging ATPase Journal Article Review

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K Ando, T Fujita. 1996. [Essential hypertension].. https://pubmed.ncbi.nlm.nih.gov/8904235/

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