Arterial input functions from MR phase imaging.

E Akbudak; T E Conturo

doi:10.1002/mrm.1910360602

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Arterial input functions from MR phase imaging.

E Akbudak·T E Conturo

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Abstract

A method is presented for obtaining high-sensitivity arterial input functions following bolus intravenous contrast agent administration. Arterial contrast agent is monitored by phase reconstruction of single-shot echo-planar images. During bolus injections of a gadolinium (Gd) agent in a baboon, data were acquired at the mid-abdominal aorta, and magnitude and phase-shift images were reconstructed. Pairwise image subtraction was used to minimize phase aliasing. The phase-based method is shown to have a significant potential improvement in sensitivity compared to the magnitude approach. The phase method also has a general linear response to concentration. This method may have potential utility in quantitative imaging of blood flow and contrast agent kinetics.

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Animals Aorta, Abdominal Blood Flow Velocity Female Infusions, Intravenous Magnetic Resonance Angiography Papio Pentetic Acid Sensitivity and Specificity Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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E Akbudak, T E Conturo. 1996. Arterial input functions from MR phase imaging.. https://doi.org/10.1002/mrm.1910360602

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