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Parallel computation enables precise description of Ca2+ distribution in nerve terminals.

S Aharon·M Bercovier·H Parnas
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Abstract

Parallel computation employing a domain decomposition method was used to calculate precisely without approximations the spatio-temporal distribution of Ca2+ in nerve terminals. The results showed, contrary to expectations, that for equal admitted Ca2+ currents at low (one channel open) and high (four channels open) depolarization, the average Ca2+ concentration at the release area is higher at the low depolarization. These calculations provide additional support for the Ca(2+)-voltage hypothesis for neurotransmitter release.

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AnimalsCalciumMathematicsMembrane PotentialsModels, NeurologicalNerve EndingsNeurotransmitter AgentsJournal Article

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S Aharon, M Bercovier, H Parnas. 1996. Parallel computation enables precise description of Ca2+ distribution in nerve terminals.. https://doi.org/10.1007/bf02458384

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