[MR-scanning in complex partial epilepsy].

T Christensen; B Pedersen; F T Jensen

Home/Archive/PubMed

PubMed · 8966792

[MR-scanning in complex partial epilepsy].

T Christensen·B Pedersen·F T Jensen

View original source ↗Export metadata ↓

Abstract

In a prospective investigation concerning 50 consecutive patients suffering from complex partial epilepsy who all had a normal CT investigation pathological findings were recognized in 80% using MRI. The MRI examination included volume estimation of the hippocampus. The volume estimations were compared to a reference material. In 24% a focal pathology was recognized, that was suspected of being responsible for the epileptic condition. Only 20% of the examinations were evaluated as normal. Hippocampal atrophy was recognized in 50%. In the latter group a diagnosis of hippocampal sclerosis was established in 16%. It is concluded that MRI is the investigation of choice in complex partial epilepsy and that volume estimation of the hippocampus is important.

Explore related subjects

Epilepsies, Partial Hippocampus Humans Magnetic Resonance Imaging Prospective Studies English Abstract Journal Article

Keep this discovery

Explore connections, maps & timelines

BibTeX RIS

T Christensen, B Pedersen, F T Jensen. 1996-09-30. [MR-scanning in complex partial epilepsy].. https://pubmed.ncbi.nlm.nih.gov/8966792/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1998

[Familial benign partial epilepsy of early infancy].

INTRODUCTION AND CLINICAL CASES: We present two patients who at the ages of 5 and 17 months respectively presented with convulsive crises with motor signs, of partial onset and secondary generalization, which eventually became normal. Both patients had a family history of first degree relatives with similar illnesses and are at present-five years later-well and with normal development, school achievement and neurological examination findings. The clinical characteristics, normal biochemical and neuroimaging investigations and EEG characteristics suggest the diagnosis of benign partial epilepsy of early infancy. This syndrome is characterized by its appearance during the first year of life, having no known etiological factors, with partial crises occurring several times a day and with a course leading to remission. Its frequency may be greater than is thought. There is a pattern of dominant autosomal inheritance, with a gene recently found on chromosome 19. CONCLUSION: We consider that this syndrome should be included in the International Classification of Epilepsy and Epileptic Syndromes as benign familial idiopathic partial epilepsy.

Epilepsies, Partial↗

PubMed1998

Aspects of proton MR spectroscopy in the seizure patient.

Seizures, especially epileptic seizures, are among the most common neurologic symptoms. They may occur as a result of fever, hypoglycemia, or acute central nervous system infections. This article discusses how MR imaging and MR spectroscopy contribute to the management of the epileptic patient.

Epilepsies, Partial↗

PubMed1997

Spatiotemporal stationarity of epileptic focal activity evaluated by analyzing magnetoencephalographic (MEG) data and the theoretical implications.

BACKGROUND: The emitted brain neuromagnetic activity was recorded from patients suffering from idiopathic epilepsy, using a Superconductive Quantum Interference Device (SQUID). This activity will be referred as magnetoencephalogram (MEG). METHODS: The MEG recording which were obtained from 32 equal spaced points of a rectangular 4 x 8 matrix were analysed using Fourier statistical analysis. Then, a two dimensional brain mapping technique was utilized in order to detect the possible existence and the accurate localization of epileptic foci. The applied technique was based on the construction of ISO contour maps which are lines of equal power spectral amplitudes of the scalp spatial distribution of the recorded MEGs specific frequency bands. These maps will be referred as ISO-SA maps. A number of more than 200 epileptic patients were examined using this method. For each patient the magnetic brain activity was recorded for the temporal lobes, the frontal lobe and the occipital lobe. ISO-SA mappings were reconstructed for the frequency bands of the compound delta and theta rhythms (2-7 Hz), the alpha rhythm (8-13 Hz), and the beta rhythm (14-25 Hz). In these mappings epileptic (pathological) foci are represented as points emitting abnormal high magnetic power in the frequency band of 2-7 Hz. RESULTS: Systematic MEG measurements showed that the abnormal activity of a certain cortex region, when present, is stationary, i.e., time-invariant. CONCLUSIONS: Brain magnetic fields on the order of magnitude a picotesia are considered as to their possible physiologic nature, and a query is made as to what physical mechanisms might be involved in this propitiation.

Epilepsies, Partial↗