Do macrophages kill through apoptosis?

A O Aliprantis; G Diez-Roux; L C Mulder; A Zychlinsky; R A Lang

doi:10.1016/s0167-5699(96)10071-2

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PubMed · 8991289

Do macrophages kill through apoptosis?

A O Aliprantis·G Diez-Roux·L C Mulder·A Zychlinsky·R A Lang

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Abstract

Macrophages can kill target cells independent of conventional immune specificity. Based on a re-examination of literature three decades old and recent experiments, Antonios Aliprantis and colleagues propose that macrophages kill target cells by inducing apoptosis. For this purpose, macrophages employ a selection of pro-apoptotic mediators including reactive oxygen and nitrogen species and tumour necrosis factor alpha.

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Animals Apoptosis Cytotoxicity, Immunologic Humans Macrophages Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.Review

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A O Aliprantis, G Diez-Roux, L C Mulder, A Zychlinsky, R A Lang. 1996. Do macrophages kill through apoptosis?. https://doi.org/10.1016/s0167-5699(96)10071-2

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