Genome research and evolution in trypanosomes.

J E Donelson

doi:10.1016/s0959-437x(96)80023-2

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Genome research and evolution in trypanosomes.

J E Donelson

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Abstract

Trypanosoma brucei and Trypanosoma cruzi cause different human diseases. As strategies for immune evasion, T. brucei undergone antigenic variation whereas T. cruzi becomes an intracellular organism. This fundamental difference is reflected by major differences in their genome organizations. Recent comparisons of their gene sequences indicate that these two trypanosome species are highly divergent evolutionarily.

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Animals Evolution, Molecular Genome, Protozoan Humans RNA Editing RNA, Protozoan Trypanosoma brucei brucei Trypanosoma cruzi Journal Article Review

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J E Donelson. 1996. Genome research and evolution in trypanosomes.. https://doi.org/10.1016/s0959-437x(96)80023-2

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