Nucleic acid based sensors.

F F Bier; J P Fürste

doi:10.1007/978-3-0348-9043-4_7

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PubMed · 9002209

Nucleic acid based sensors.

F F Bier·J P Fürste

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Abstract

Nucleic acids may be analyte or molecular recognition elements in biosensors. Both aspects merge in the genosensor approach, where detection of special sequences is facilitated by hybridization of a target nucleic acid to a complementary immobilized template. All three roles of nucleic acids in biosensors are discussed and the state of sensor development reviewed. With the invention of evolutionary synthesis strategies applied to nucleic acids new types of biomolecular receptors are accessible. The impact of aptamers and ribozymes on biosensor development is discussed.

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Adsorption Biosensing Techniques DNA Probes DNA-Binding Proteins Electrochemistry Fluorescent Dyes Kinetics Nucleic Acid Hybridization Nucleic Acids RNA RNA, Catalytic RNA-Binding Proteins Templates, Genetic Journal Article

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F F Bier, J P Fürste. 1997. Nucleic acid based sensors.. https://doi.org/10.1007/978-3-0348-9043-4_7

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