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PubMed · 9022199

Proton dosimetry in bone using electron spin resonance.

J F Copeland·K P Gall·S Y Lee·G E Chabot
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Abstract

We have studied the ESR response of proton-irradiated (in vitro) bone. The ESR response as a function of proton (E = 105 MeV) dose to bone was linear from 0 to 50 Gy and similar to the photon (E = 6 MV) dose response. The ESR depth response (Bragg) curve was depressed as compared to a depth-response curve determined with a parallel plate ionization chamber (PPIC). There was a short-term ESR signal fade in the Bragg peak region, likely attributable to the organic component in bone. We are continuing to investigate these latter two effects.

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Bone and BonesElectron Spin Resonance SpectroscopyHumansIn Vitro TechniquesPhantoms, ImagingProton TherapyRadiometryRadiotherapy DosageRadiotherapy, High-EnergyProtonsJournal ArticleResearch Support, U.S. Gov't, Non-P.H.S.Research Support, U.S. Gov't, P.H.S.

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J F Copeland, K P Gall, S Y Lee, G E Chabot. Proton dosimetry in bone using electron spin resonance.. https://doi.org/10.1016/s0969-8043(96)00246-1

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