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PubMed · 9039621

Dual dynamic contrast-enhanced MR imaging.

T Miyati·T Banno·M Mase·H Kasai·H Shundo·M Imazawa·S Ohba
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Abstract

A method was devised for obtaining dynamic contrast-enhanced T1-weighted and relaxation rate (delta R2*) images simultaneously to evaluate regional hemodynamics of the brain tumors. On a 1.5-T MR system, dual dynamic contrast-enhanced images were obtained using a gradient echo (dual echo fast field echo) pulse sequence with the keyhole technique to improve temporal and spatial resolution during a rapid bolus injection of gadopentetate dimeglumine. The dynamic T1 contrast images were obtained from the first echo: moreover. integral delta R2*dt values were calculated from the first and the second echo images. The dynamic T1 contrast images provided information about characteristic enhancement pattern (vascularization and disruption of blood-brain barrier), and the integral delta R2*dt values provided a map of regional blood pool in tumor site, peritumoral edema, and other surrounding regions of the brain. The ability to obtain dynamic contrast-enhanced T1 contrast and delta R2* imaging at the same time allows optimization of the advantages of each and thereby more information about the microvascular circulation of the brain lesions.

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BrainBrain NeoplasmsContrast MediaDiagnosis, DifferentialHemodynamicsHumansImage EnhancementMagnetic Resonance AngiographyMagnetic Resonance ImagingSensitivity and SpecificitySpinal Cord NeoplasmsJournal Article

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T Miyati, T Banno, M Mase, H Kasai, H Shundo, M Imazawa, S Ohba. Dual dynamic contrast-enhanced MR imaging.. https://doi.org/10.1002/jmri.1880070136

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