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MHC class I and class II structures.

E Y Jones
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Abstract

The basic structures of MHC class I and class II molecules are now well established. Over the past twelve months structural data on MHC class I molecules have provided details of the peptide binding groove for a number of alleles and have elaborated the mechanisms that allow binding of a range of peptides. Recent MHC class II structures have illustrated the mode of peptide binding both in mature complexes and in the MHC class II complex with a fragment of invariant chain (CLIP) during maturation.

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AnimalsHistocompatibility Antigens Class IHistocompatibility Antigens Class IIHumansProtein ConformationStructure-Activity RelationshipJournal ArticleReview

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BibTeXRIS

E Y Jones. 1997. MHC class I and class II structures.. https://doi.org/10.1016/s0952-7915(97)80162-8

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