Origin, maturation and antigen presenting function of dendritic cells.

M Cella; F Sallusto; A Lanzavecchia

doi:10.1016/s0952-7915(97)80153-7

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Origin, maturation and antigen presenting function of dendritic cells.

M Cella·F Sallusto·A Lanzavecchia

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Abstract

Dendritic cells are cells specialized for antigen capture, migration and T cell stimulation. Recent advances have been made in understanding their origin, their heterogeneity, the mechanism of antigen uptake, and the signals that induce their migration and maturation into immunostimulatory antigen-presenting cells. Dendritic cells represent the natural adjuvants for T cell responses and their therapeutic exploitation in the near future is foreseen.

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Animals Antigen Presentation Cell Differentiation Dendritic Cells Humans Journal Article Research Support, Non-U.S. Gov't Review

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M Cella, F Sallusto, A Lanzavecchia. 1997. Origin, maturation and antigen presenting function of dendritic cells.. https://doi.org/10.1016/s0952-7915(97)80153-7

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