PubMed · 9043339
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D Payne. The compromised land.. https://pubmed.ncbi.nlm.nih.gov/9043339/
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A deletion mutation of 8.6Kb in the CFTR gene, spanning the exons 17a, 17b and 18 was identified in 4 homozygous unrelated Palestinian CF patients. The patients were of various ethnic subgroups including Muslims, Christians and Druze. The deletion breakpoint occurred within an identical 4bp sequence in introns 16 and 18, and the mutation was defined as 3120+1Kbdel8.6Kb. A simple PCR based assay was designed and using this assay two compound heterozygote patients with the 3120+1Kbdel8.6Kb were identified. The 3120+1Kbdel8.6Kh hearing chromosomes had a common intragenic haplotype and variable flanking polymorphic markers, indicating that it is an ancient founder mutation.
This study investigated the effect of Arabic vowels on the reading comprehension of native Arabic speakers. This issue has not been addressed yet. Two groups of native Arabic speakers were randomly sampled, one from two elementary schools in the Haifa area, and the other from two elementary schools in Nazareth. Both groups in both experiments read Arabic texts in two reading conditions, vowelized and unvowelized; the older group (n = 74) answered 10 multiple-choice comprehension questions about each story, and the younger group (n = 71) answered seven multiple-choice comprehension questions. The results revealed that vowels were a significant facilitator of reading comprehension in both age groups. Considering these results, reading in Arabic orthography is not an autonomous word recognition process. An alternative approach is suggested for reading Arabic.