PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 9064797

[Quality control in ultrasonography].

J Y Meuwly
View original source ↗Export metadata ↓

Abstract

Because of the lack of resources, which is getting more and more important, the control of quality is becoming an important consideration in the health system. The ultrasound as a cheap and easily available tool is no exception in this consideration. The control of the technical quality must follow certain considerations, which must be anchored in the daily usage. This is especially important if we want to evaluate the effect of the ultrasound diagnostic on the further development of the patient, the general health status, the quality of life of a certain population with large-scale epidemiologic studies. If the interpretation and indication of ultrasound should be part of medical knowledge and training, the technical quality control should also be part of the basic duties regularly done. The technical quality is the first part of the chain of the diagnostic by ultrasound. The slightest disturbance will certainly have consequences in the following steps of the treatment of the patient. The evaluation of the quality must contain a control of the security of the technical equipment available, of the spatial and contrast resolution of all the ultrasound transducers as well as a control of the monitor. Testing of the resolution can be done with a specially designed simulator/phantom, equipped with special marks permitting the measuring of the axial, lateral and transversal resolution, this simulator is also used in planimetry to evaluate the region of the optimal resolution and the geometrical reproduction. These controls must be done regularly, and the data received must be stored. Only with such a regular control we can guarantee the quality of the technical equipment and installations.

Explore related subjects

HumansQuality Assurance, Health CareReference ValuesSignal Processing, Computer-AssistedUltrasonographyEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

J Y Meuwly. 1997. [Quality control in ultrasonography].. https://pubmed.ncbi.nlm.nih.gov/9064797/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2027

Global Genomic Surveillance.

Global genomic surveillance has emerged as a foundational pillar of public health in the twenty-first century, enabling real-time tracking of pathogen evolution and informing outbreak response. This chapter examines the strategic architecture of global genomic surveillance, focusing on its application to arboviruses such as chikungunya virus (CHIKV). It explores the integration of genomic data with epidemiological, clinical, and environmental information within a One Health framework, while addressing critical challenges in governance, equity, and interoperability. The discussion covers the entire genomic surveillance workflow, from sample collection and sequencing to bioinformatic analysis and phylogenetic inference, and highlights the transformative role of artificial intelligence (AI) in predictive surveillance. By analyzing global initiatives, operational barriers, and emerging technologies, this chapter underscores the necessity of sustainable, equitable, and interoperable genomic systems to proactively address current and future infectious disease threats.

Humans↗
PubMed2027

Systematic Dissection of Key Driver Perturbation Signatures in Single Cells via ECCITE-seq.

CRISPR screens, such as expanded CRISPR-compatible cellular indexing of transcriptomes and epitopes by sequencing (ECCITE-seq), enable the simultaneous measurement of transcriptomes, gRNA identity, and cell-surface protein expression at single-cell resolution to systematically interrogate gene function. This platform provides a powerful and scalable experimental approach for validating disease-associated regulators identified by large-scale association studies and other computational methods, including network-based analyses of multi-omics data. Here, as an example application, we describe an ECCITE-seq framework to characterize the transcriptomic consequences of perturbing multiple neuronal key driver genes associated with Alzheimer's disease (AD) in human-induced pluripotent stem cell (hiPSC)-derived neurons. More broadly, by integrating customized pooled gRNA libraries with different CRISPR effectors across multiple cell types, this approach allows for the assessment of the regulatory impact of candidate genes implicated in development and disease processes.

Humans↗
PubMed2027

Identification of Genome-Wide Chromatin Structural Aberration in Cancer by Hi-C Analysis.

Aberrant three-dimensional genome organization is a hallmark of cancer, often driving oncogene activation through mechanisms such as enhancer hijacking. High-throughput chromosome conformation capture (Hi-C) maps these interactions on a genome-wide scale. Unlike earlier dilution-based methods, in situ Hi-C performs proximity ligation within intact nuclei, minimizing random ligation noise and enabling fine-scale structure detection. This chapter describes an optimized in situ Hi-C protocol tailored for cancer cell lines using MboI digestion and biotin-mediated pull-down to generate high-complexity libraries. We further outline a computational workflow that extends beyond standard topological mapping of compartments and topologically associating domains to identify cancer-specific aberrations. Specifically, we focus on detecting chromosomal rearrangements (structural variants) and characterizing the distinct circular topology of extrachromosomal DNA. This integrated experimental and analytical framework provides the necessary tools to dissect the spatial dysregulation underlying tumor evolution.

Humans↗