T-cell receptors: feeling out the complex.

E A Padlan; D H Marguilies

doi:10.1016/s0960-9822(06)00010-8

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PubMed · 9072162

T-cell receptors: feeling out the complex.

E A Padlan·D H Marguilies

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Abstract

Recent crystallographic studies show that the T-cell receptor has a largely immunoglobulin-like structure and binds to MHC-peptide complexes through loops from paired Valpha and Vbeta domains that focus on the central amino acids of the MHC-bound peptide, and to bacterial superantigens via peripheral aspects of the Vbeta domain.

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Humans Immunoglobulins Major Histocompatibility Complex Receptors, Antigen, T-Cell Journal Article

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E A Padlan, D H Marguilies. 1997-01-01. T-cell receptors: feeling out the complex.. https://doi.org/10.1016/s0960-9822(06)00010-8

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