Cellular correlates to spatial learning in the rat hippocampus.

P Andersen; E Moser; M B Moser; M Trommald

doi:10.1016/s0928-4257(97)87917-x

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PubMed · 9089511

Cellular correlates to spatial learning in the rat hippocampus.

P Andersen·E Moser·M B Moser·M Trommald

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Abstract

Learning through exploration gives increased synaptic field potentials in the perforant path/dentate synapses, largely due to an activity-dependent brain temperature increase. After temperature compensation, spatial learning was associated with small, but significant, STP-like changes of the field potential lasting 20-30 min. A group of spatially trained adult rats showed faster spatial learning and about 10% higher basal dendritic spine density (LY-filled) compared to two control groups. With unchanged dendritic length and branching pattern, the results suggest the formation of new synapses.

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Animals Dendrites Dentate Gyrus Exploratory Behavior Hippocampus Learning Long-Term Potentiation Neuronal Plasticity Neurons Pyramidal Cells Rats Space Perception Synapses Synaptic Transmission Journal Article

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P Andersen, E Moser, M B Moser, M Trommald. 1996. Cellular correlates to spatial learning in the rat hippocampus.. https://doi.org/10.1016/s0928-4257(97)87917-x

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