Advances in gene targeting methods.

R Kühn; F Schwenk

doi:10.1016/s0952-7915(97)80133-1

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Advances in gene targeting methods.

R Kühn·F Schwenk

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Abstract

Gene targeting in embryonic stem cells is commonly used for gene inactivation and the generation of mouse mutants. The combined use of methods for site-specific and homologous DNA recombination expands the potential of gene targeting in embryonic stem cells considerably and offers the opportunity of conditional gene targeting in mice.

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Animals Gene Targeting Mice Mice, Mutant Strains Journal Article Review

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R Kühn, F Schwenk. 1997. Advances in gene targeting methods.. https://doi.org/10.1016/s0952-7915(97)80133-1

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