Long-term memory modulation by posttraining epinephrine in rats: differential effects depending on the basic learning capacity.

M Torras-Garcia; I Portell-Cortés; D Costa-Miserachs; I Morgado-Bernal

doi:10.1037//0735-7044.111.2.301

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Long-term memory modulation by posttraining epinephrine in rats: differential effects depending on the basic learning capacity.

M Torras-Garcia·I Portell-Cortés·D Costa-Miserachs·I Morgado-Bernal

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Abstract

Effects of posttraining epinephrine on retention of a massed (1 session, 30 trials) 2-way active avoidance task were studied in rats. Immediately after the training session rats received an injection of 0.05 or 0.01 mg/kg ip epinephrine, or distilled water. Retention was tested 11, 20, or 45 days after training, in independent groups of rats. The 20- and 45-day retention was improved in poor-learning rats and disrupted in good-learning rats. It was concluded that the effect (facilitatory or disruptive) of posttraining epinephrine on memory consolidation depends on the basic learning capacity of rats for this task and needs a long time to be expressed.

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Animals Avoidance Learning Brain Dose-Response Relationship, Drug Epinephrine Injections, Intraperitoneal Male Rats Rats, Wistar Retention, Psychology Journal Article Research Support, Non-U.S. Gov't

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M Torras-Garcia, I Portell-Cortés, D Costa-Miserachs, I Morgado-Bernal. 1997. Long-term memory modulation by posttraining epinephrine in rats: differential effects depending on the basic learning capacity.. https://doi.org/10.1037/%2F0735-7044.111.2.301

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